River-valley lodge between the Appalachian Mountains pairs meals with local wines & offers fishing, disc-golfing & ziplining

Culinary vacation delves into southern cuisine & Virginian wines through winery tour, five-course dinner & classes with chef

Manor house built in 1735 anchors 250-acre resort home to private condos, swimming pools & outdoor activities

18-hole golf course highlights resort with natural-stone fireplaces & balconies overlooking Bristol Mountains & Canandaigua Lake

Personal trainers & nutrition counselors set up motivational workouts & customized meal plans at luxurious Jordan Ranch Lodge

Re-created frontier town sprawling 272 acres sets backdrop for gourmet dinner, themed hotel rooms & sunset horseback rides through desert

Ski resort near Canadian Rockies features groomed terrain parks, powdery bowls & sprawling base village with restaurants & shops

Soaring glass atrium, restaurants & spa at AAA Four Diamond hotel on banks of Potomac, just south of DC

Eleven-day guided safari explores northern Tanzania's Serengeti in search of wildebeests, giraffes, elephants & other big game

Full-service spa & indoor pool at sprawling resort on Lake Rousseau, where snowshoers & snowmobilers cut across hundreds of woodland acres